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Population Pharmacokinetic Modeling of Tenofovir in the Genital Tract of Male HIV-Infected Patients

The aims of this study were to describe the blood plasma (BP) and seminal plasma (SP) pharmacokinetics of tenofovir (TFV) in HIV-1-infected men, to assess the role of genetic polymorphism in the variability of TFV transfer into the male genital tract, and to evaluate the impact of TFV SP exposure on...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Valade, Elodie, Bouazza, Naïm, Lui, Gabrielle, Illamola, Silvia M., Benaboud, Sihem, Treluyer, Jean-Marc, Cobat, Aurélie, Foissac, Frantz, De Sousa Mendes, Maïlys, Chenevier-Gobeaux, Camille, Suzan-Monti, Marie, Rouzioux, Christine, Assoumou, Lambert, Viard, Jean-Paul, Urien, Saïk, Ghosn, Jade, Hirt, Déborah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328554/
https://ncbi.nlm.nih.gov/pubmed/27956420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02062-16
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