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Pharmacokinetics/Pharmacodynamics of Pulmonary Delivery of Colistin against Pseudomonas aeruginosa in a Mouse Lung Infection Model

Colistin is often administered by inhalation and/or the parenteral route for the treatment of respiratory infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa. However, limited pharmacokinetic (PK) and pharmacodynamic (PD) data are available to guide the optimization of dosage regim...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Lin, Yu-Wei, Zhou, Qi Tony, Cheah, Soon-Ee, Zhao, Jinxin, Chen, Ke, Wang, Jiping, Chan, Hak-Kim, Li, Jian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328518/
https://ncbi.nlm.nih.gov/pubmed/28031207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02025-16
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