Pharmacokinetics of Miltefosine in Children and Adults with Cutaneous Leishmaniasis

An open-label pharmacokinetics (PK) clinical trial was conducted to comparatively assess the PK and explore the pharmacodynamics (PD) of miltefosine in children and adults with cutaneous leishmaniasis (CL) in Colombia. Sixty patients, 30 children aged 2 to 12 years and 30 adults aged 18 to 60 years,...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Castro, María del Mar, Gomez, Maria Adelaida, Kip, Anke E., Cossio, Alexandra, Ortiz, Eduardo, Navas, Adriana, Dorlo, Thomas P. C., Saravia, Nancy Gore
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328512/
https://ncbi.nlm.nih.gov/pubmed/27956421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02198-16
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