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Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis

Exposure to blood-stage malaria infection is often persistent, leading to generation of CD4 effector and effector memory T cells that contribute to protection. We showed previously that chronic exposure to blood-stage Plasmodium chabaudi offers the best protection from parasitemia and pathology in r...

詳細記述

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書誌詳細
出版年:Infect Immun
主要な著者: Opata, Michael M., Stephens, Robin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328498/
https://ncbi.nlm.nih.gov/pubmed/28031266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00744-16
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