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Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis

Exposure to blood-stage malaria infection is often persistent, leading to generation of CD4 effector and effector memory T cells that contribute to protection. We showed previously that chronic exposure to blood-stage Plasmodium chabaudi offers the best protection from parasitemia and pathology in r...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Opata, Michael M., Stephens, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328498/
https://ncbi.nlm.nih.gov/pubmed/28031266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00744-16
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