Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity

Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to recurrence and drug resistance following therapy. Genome-wide profiling has revealed the existence of distinct GBM molecular subtypes that respond differently to aggressive therapies. Despite this, molecular subtyp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brown, Daniel V., Filiz, Gulay, Daniel, Paul M., Hollande, Frédéric, Dworkin, Sebastian, Amiridis, Stephanie, Kountouri, Nicole, Ng, Wayne, Morokoff, Andrew P., Mantamadiotis, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328356/
https://ncbi.nlm.nih.gov/pubmed/28241049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172791
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