Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPD

Skeletal muscle atrophy and dysfunction are common complications in the chronic obstructive pulmonary disease (COPD). However, the underlying molecular mechanism remains elusive. Serum response factor (SRF) is a transcription factor which is critical in myocyte differentiation and growth. In this st...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Ma, Ran, Gong, Xuefang, Jiang, Hua, Lin, Chunyi, Chen, Yuqin, Xu, Xiaoming, Zhang, Chenting, Wang, Jian, Lu, Wenju, Zhong, Nanshan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327903/
https://ncbi.nlm.nih.gov/pubmed/28260872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S109243
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