ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma

Glioblastoma is associated with poor survival and a high recurrence rate in patients due to inevitable uncontrolled infiltrative tumor growth. The elucidation of the molecular mechanisms may offer opportunities to prevent relapses. In this study we investigated the role of the activating transcripti...

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Veröffentlicht in:Cell Death Discov
Hauptverfasser: Guenzle, Jessica, Wolf, Louisa J, Garrelfs, Nicklas W C, Goeldner, Jonathan M, Osterberg, Nadja, Schindler, Cora R, Saavedra, Joseph E, Weyerbrock, Astrid
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327503/
https://ncbi.nlm.nih.gov/pubmed/28250971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.6
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