ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma

Glioblastoma is associated with poor survival and a high recurrence rate in patients due to inevitable uncontrolled infiltrative tumor growth. The elucidation of the molecular mechanisms may offer opportunities to prevent relapses. In this study we investigated the role of the activating transcripti...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Guenzle, Jessica, Wolf, Louisa J, Garrelfs, Nicklas W C, Goeldner, Jonathan M, Osterberg, Nadja, Schindler, Cora R, Saavedra, Joseph E, Weyerbrock, Astrid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327503/
https://ncbi.nlm.nih.gov/pubmed/28250971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.6
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