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Metal binding mediated conformational change of XPA protein: a potential cytotoxic mechanism of nickel in the nucleotide excision repair

Nucleotide excision repair (NER) is a pivotal life process for repairing DNA nucleotide mismatch caused by chemicals, metal ions, radiation, and other factors. As the initiation step of NER, the xeroderma pigmentosum complementation group A protein (XPA) recognizes damaged DNA molecules, and recruit...

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Bibliografische gegevens
Gepubliceerd in:J Mol Model
Hoofdauteurs: Hu, Jianping, Hu, Ziheng, Zhang, Yan, Gou, Xiaojun, Mu, Ying, Wang, Lirong, Xie, Xiang-Qun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327499/
https://ncbi.nlm.nih.gov/pubmed/27307058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-016-3017-x
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