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Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets

ABSTRACT: BACKGROUND: Diffuse Intrinsic Pontine Glioma (DIPG) is the leading cause of brain tumor-related death in children, with median survival of less than one year. Despite decades of clinical trials, there has been no improvement in prognosis since the introduction of radiotherapy over thirty y...

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Detalhes bibliográficos
Publicado no:Curr Neuropharmacol
Main Authors: Johung, Tessa B., Monje, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327455/
https://ncbi.nlm.nih.gov/pubmed/27157264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666160509123229
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