Hypoxia-Inducible Factor-1α Target Genes Contribute to Retinal Neuroprotection

Hypoxia-inducible factor (HIF) is a transcription factor that facilitates cellular adaptation to hypoxia and ischemia. Long-standing evidence suggests that one isotype of HIF, HIF-1α, is involved in the pathogenesis of various solid tumors and cardiac diseases. However, the role of HIF-1α in retina...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Cheng, Lin, Yu, Honghua, Yan, Naihong, Lai, Kunbei, Xiang, Mengqing
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326762/
https://ncbi.nlm.nih.gov/pubmed/28289375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00020
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