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Rosiglitazone-activated PPARγ induces Neurotrophic Factor-α1 Transcription contributing to Neuroprotection

Brain peroxisome proliferator-activated receptor gamma (PPARγ), a member of the nuclear receptor superfamily of ligand-dependent transcription factors, is involved in neuroprotection. It is activated by the drug rosiglitazone, which then can increase the prosurvival protein BCL-2, to mediate neuropr...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Thouennon, Erwan, Cheng, Yong, Falahatian, Vida, Cawley, Niamh X., Loh, Y. Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496294/
https://ncbi.nlm.nih.gov/pubmed/25940785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13152
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