Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung

The capacity of CD4 T cells to protect against Mycobacterium tuberculosis (Mtb) is governed by their ability to localize to the lung site of infection. Subunit vaccine H56/CAF01, a liposome-adjuvanted fusion protein of Mtb antigens Ag85B, ESAT-6, and Rv2660, conferred durable protection and elicited...

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Vydáno v:Mucosal Immunol
Hlavní autoři: Woodworth, Joshua S., Cohen, Sara B., Moguche, Albanus O., Plumlee, Courtney R., Agger, Else Marie, Urdahl, Kevin B., Andersen, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325828/
https://ncbi.nlm.nih.gov/pubmed/27554293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.70
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