Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

Mucins are heavily glycosylated proteins that give mucus its gel-like properties. Moreover, the glycans decorating the mucin protein core can alter the protective properties of the mucus barrier. To investigate whether these alterations could be parasite-induced we utilized the Trichuris muris (T. m...

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Опубликовано в: :PLoS Pathog
Главные авторы: Hasnain, Sumaira Z., Dawson, Paul A., Lourie, Rohan, Hutson, Peter, Tong, Hui, Grencis, Richard K., McGuckin, Michael A., Thornton, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325613/
https://ncbi.nlm.nih.gov/pubmed/28192541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006218
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