Species dependent impact of helminth-derived antigens on human macrophages infected with Mycobacterium tuberculosis: Direct effect on the innate anti-mycobacterial response

BACKGROUND: In countries with a high prevalence of tuberculosis there is high coincident of helminth infections that might worsen disease outcome. While Mycobacterium tuberculosis (Mtb) gives rise to a pro-inflammatory Th1 response, a Th2 response is typical of helminth infections. A strong Th2 resp...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Aira, Naomi, Andersson, Anna-Maria, Singh, Susmita K., McKay, Derek M., Blomgran, Robert
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325601/
https://ncbi.nlm.nih.gov/pubmed/28192437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005390
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