Lipocalin 2 over-expression facilitates progress of castration-resistant prostate cancer via improving androgen receptor transcriptional activity

BACKGROUND: Castration-resistant prostate cancer (CRPC) is the lethal phenotype of prostate cancer. Lipocalin 2 (LCN2) is aberrantly expressed in many cancers including primary prostate cancer (PCa), but its role in CRPC has not been reported. RESULTS: LCN2 expression was upregulated in human primar...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Ding, Guanxiong, Wang, Jianqing, Feng, Chenchen, Jiang, Haowen, Xu, Jianfeng, Ding, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325444/
https://ncbi.nlm.nih.gov/pubmed/27602760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11790
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