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Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination

The efficacy of pharmacological perturbation to the signaling transduction network depends on the network topology. However, whether and how signaling dynamics mediated by crosstalk contributes to the drug resistance are not fully understood and remain to be systematically explored. In this study, m...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Sun, Xiaoqiang, Bao, Jiguang, You, Zhuhong, Chen, Xing, Cui, Jun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325420/
https://ncbi.nlm.nih.gov/pubmed/27590512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11745
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