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Cytokine Combination Therapy Prediction for Bone Remodeling in Tissue Engineering Based on the Intracellular Signaling Pathway

The long-term performance of tissue-engineered bone grafts is determined by a dynamic balance between bone regeneration and resorption. We proposed using embedded cytokine slow-releasing hydrogels to tune this balance toward a desirable final bone density. In this study we established a systems biol...

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Bibliographic Details
Main Authors: Sun, Xiaoqiang, Su, Jing, Bao, Jiguang, Peng, Tao, Zhang, Le, Zhang, Yuanyuan, Yang, Yunzhi, Zhou, Xiaobo
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444627/
https://ncbi.nlm.nih.gov/pubmed/22910219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.07.041
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