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Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination
The efficacy of pharmacological perturbation to the signaling transduction network depends on the network topology. However, whether and how signaling dynamics mediated by crosstalk contributes to the drug resistance are not fully understood and remain to be systematically explored. In this study, m...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325420/ https://ncbi.nlm.nih.gov/pubmed/27590512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11745 |
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