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Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination

The efficacy of pharmacological perturbation to the signaling transduction network depends on the network topology. However, whether and how signaling dynamics mediated by crosstalk contributes to the drug resistance are not fully understood and remain to be systematically explored. In this study, m...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Sun, Xiaoqiang, Bao, Jiguang, You, Zhuhong, Chen, Xing, Cui, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325420/
https://ncbi.nlm.nih.gov/pubmed/27590512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11745
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