Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: antitumor activity in mouse melanoma models

ALOS4, a unique synthetic cyclic peptide without resemblance to known integrin ligand sequences, was discovered through repeated biopanning with pIII phage expressing a disulfide-constrained nonapeptide library. Binding assays using a FITC-labeled analogue demonstrated selective binding to immobiliz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Yacobovich, Shiri, Tuchinsky, Lena, Kirby, Michael, Kardash, Tetiana, Agranyoni, Oryan, Nesher, Elimelech, Redko, Boris, Gellerman, Gary, Tobi, Dror, Gurova, Katerina, Koman, Igor, Fabian, Osnat Ashur, Pinhasov, Albert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325384/
https://ncbi.nlm.nih.gov/pubmed/27556860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11363
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