Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer

Radio- and chemo-resistance represent major obstacles in the therapy of non-small-cell lung cancer (NSCLC) and the underlying molecular mechanisms are not known. In the present study, during induction of radio- or chemo-resistance in NSCLC cells, dynamic analyses revealed that decreased expression o...

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Publicado en:PLoS One
Autores principales: Yin, Jun, Zhao, Jian, Hu, Weimin, Yang, Guangping, Yu, Hui, Wang, Ruihao, Wang, Linjing, Zhang, Guoqian, Fu, Wenfan, Dai, Lu, Li, Wanzhen, Liao, Boyu, Zhang, Shuxu
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325287/
https://ncbi.nlm.nih.gov/pubmed/28235063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172787
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