Critical role of intestinal interleukin-4 modulating regulatory T cells for desensitization, tolerance, and inflammation of food allergy

BACKGROUND AND OBJECTIVE: The mechanism inducing either inflammation or tolerance to orally administered food allergens remains unclear. To investigate this we analyzed mouse models of food allergy (OVA23-3) and tolerance (DO11.10 [D10]), both of which express ovalbumin (OVA)-specific T-cell recepto...

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Pubblicato in:PLoS One
Autori principali: Nakajima-Adachi, Haruyo, Shibahara, Kyoko, Fujimura, Yoko, Takeyama, Jun, Hiraide, Erika, Kikuchi, Akira, Murakami, Hitoshi, Hosono, Akira, Nochi, Tomonori, Wakatsuki, Yoshio, Shimojo, Naoki, Kaminogawa, Shuichi, Sato, Ryuichiro, Kiyono, Hiroshi, Hachimura, Satoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325285/
https://ncbi.nlm.nih.gov/pubmed/28234975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172795
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