Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D(2) Receptor Subtype 1

Niacin is a well established drug used to lower cholesterol and prevent cardiovascular disease events. However, niacin also causes cutaneous flushing side effects due to release of the proresolution mediator prostaglandin D(2) (PGD(2)). Recent randomized clinical trials have demonstrated that additi...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Kong, Deping, Li, Juanjuan, Shen, Yujun, Liu, Guizhu, Zuo, Shengkai, Tao, Bo, Ji, Yong, Lu, Ankang, Lazarus, Michael, Breyer, Richard M., Yu, Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2017
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325076/
https://ncbi.nlm.nih.gov/pubmed/28057839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.238261
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