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Activation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and Hispidulin
UVA irradiation plays a role in premature aging of the skin through triggering oxidative stress-associated stimulation of matrix metalloproteinase-1 (MMP-1) responsible for collagen degradation, a hallmark of photoaged skin. Compounds that can activate nuclear factor E2-related factor 2 (Nrf2), a tr...
Zapisane w:
| Wydane w: | J Pharmacol Exp Ther |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325073/ https://ncbi.nlm.nih.gov/pubmed/28011874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.238048 |
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