Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin‐remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D

Next‐generation sequencing (NGS) was applied to 148 lung neuroendocrine tumours (LNETs) comprising the four World Health Organization classification categories: 53 typical carcinoid (TCs), 35 atypical carcinoid (ACs), 27 large‐cell neuroendocrine carcinomas, and 33 small‐cell lung carcinomas. A disc...

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Pubblicato in:J Pathol
Autori principali: Simbolo, Michele, Mafficini, Andrea, Sikora, Katarzyna O, Fassan, Matteo, Barbi, Stefano, Corbo, Vincenzo, Mastracci, Luca, Rusev, Borislav, Grillo, Federica, Vicentini, Caterina, Ferrara, Roberto, Pilotto, Sara, Davini, Federico, Pelosi, Giuseppe, Lawlor, Rita T, Chilosi, Marco, Tortora, Giampaolo, Bria, Emilio, Fontanini, Gabriella, Volante, Marco, Scarpa, Aldo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2016
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324596/
https://ncbi.nlm.nih.gov/pubmed/27873319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4853
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