Genomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumors

Gastrointestinal stromal tumors represent the most common mesenchymal tumor of the digestive tract, driven by gain‐of‐function mutations in KIT. Despite its proven benefits, half of the patients treated with imatinib show disease progression within 2 years due to secondary resistance mutations in KI...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Genes Chromosomes Cancer
Главные авторы: Takahashi, Tsuyoshi, Elzawahry, Asmaa, Mimaki, Sachiyo, Furukawa, Eisaku, Nakatsuka, Rie, Nakamura, Hiromi, Nishigaki, Takahiko, Serada, Satoshi, Naka, Tetsuji, Hirota, Seiichi, Shibata, Tatsuhiro, Tsuchihara, Katsuya, Nishida, Toshirou, Kato, Mamoru
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324566/
https://ncbi.nlm.nih.gov/pubmed/27997714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22438
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы