Negative Regulation of DNA Repair Gene (ung) Expression by the CpxR/CpxA Two-Component System in Escherichia coli K-12 and Induction of Mutations by Increased Expression of CpxR

In Escherichia coli K-12 overexpressing CpxR, transcription of the ung gene for uracil-DNA glycosylase was repressed, ultimately leading to the induction of mutation. Gel shift, DNase I footprinting, and in vitro transcription assays all indicated negative regulation of ung transcription by phosphor...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Ogasawara, Hiroshi, Teramoto, Jun, Hirao, Kiyo, Yamamoto, Kaneyoshi, Ishihama, Akira, Utsumi, Ryutaro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC532440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15576781/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.24.8317-8325.2004
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