Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity

BACKGROUND: It is known that tissue macrophages derive not only from blood monocytes but also from yolk sac or fetal liver, and the tissue of residence guides their function. When isolated, they lose tissue specific signatures, hence studies of human macrophages should be ideally done directly in th...

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Publicat a:Respir Res
Autors principals: Bazzan, Erica, Turato, Graziella, Tinè, Mariaenrica, Radu, Claudia M., Balestro, Elisabetta, Rigobello, Chiara, Biondini, Davide, Schiavon, Marco, Lunardi, Francesca, Baraldo, Simonetta, Rea, Federico, Simioni, Paolo, Calabrese, Fiorella, Saetta, Marina, Cosio, Manuel G.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324331/
https://ncbi.nlm.nih.gov/pubmed/28231829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0522-0
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