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Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity

BACKGROUND: It is known that tissue macrophages derive not only from blood monocytes but also from yolk sac or fetal liver, and the tissue of residence guides their function. When isolated, they lose tissue specific signatures, hence studies of human macrophages should be ideally done directly in th...

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Publicado en:Respir Res
Main Authors: Bazzan, Erica, Turato, Graziella, Tinè, Mariaenrica, Radu, Claudia M., Balestro, Elisabetta, Rigobello, Chiara, Biondini, Davide, Schiavon, Marco, Lunardi, Francesca, Baraldo, Simonetta, Rea, Federico, Simioni, Paolo, Calabrese, Fiorella, Saetta, Marina, Cosio, Manuel G.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324331/
https://ncbi.nlm.nih.gov/pubmed/28231829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0522-0
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