The Impact of Cruciferous Vegetable Isothiocyanates on Histone Acetylation and Histone Phosphorylation in Bladder Cancer

Cruciferous vegetable intake is associated with reduced risk of bladder cancer, yet mechanisms remain unclear. Cruciferous vegetable isothiocyanates (ITCs), namely sulforaphane (SFN) and erucin (ECN), significantly inhibit histone deacetylase (HDAC) activity in human bladder cancer cells representin...

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Bibliografiske detaljer
Udgivet i:J Proteomics
Main Authors: Abbaoui, Besma, Telu, Kelly H., Lucas, Christopher R., Thomas-Ahner, Jennifer M., Schwartz, Steven J., Clinton, Steven K., Freitas, Michael A., Mortazavi, Amir
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324139/
https://ncbi.nlm.nih.gov/pubmed/28132875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2017.01.013
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