The Impact of Cruciferous Vegetable Isothiocyanates on Histone Acetylation and Histone Phosphorylation in Bladder Cancer

Cruciferous vegetable intake is associated with reduced risk of bladder cancer, yet mechanisms remain unclear. Cruciferous vegetable isothiocyanates (ITCs), namely sulforaphane (SFN) and erucin (ECN), significantly inhibit histone deacetylase (HDAC) activity in human bladder cancer cells representin...

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Detalhes bibliográficos
Publicado no:J Proteomics
Main Authors: Abbaoui, Besma, Telu, Kelly H., Lucas, Christopher R., Thomas-Ahner, Jennifer M., Schwartz, Steven J., Clinton, Steven K., Freitas, Michael A., Mortazavi, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324139/
https://ncbi.nlm.nih.gov/pubmed/28132875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2017.01.013
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