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The Impact of Cruciferous Vegetable Isothiocyanates on Histone Acetylation and Histone Phosphorylation in Bladder Cancer

Cruciferous vegetable intake is associated with reduced risk of bladder cancer, yet mechanisms remain unclear. Cruciferous vegetable isothiocyanates (ITCs), namely sulforaphane (SFN) and erucin (ECN), significantly inhibit histone deacetylase (HDAC) activity in human bladder cancer cells representin...

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Bibliographische Detailangaben
Veröffentlicht in:J Proteomics
Hauptverfasser: Abbaoui, Besma, Telu, Kelly H., Lucas, Christopher R., Thomas-Ahner, Jennifer M., Schwartz, Steven J., Clinton, Steven K., Freitas, Michael A., Mortazavi, Amir
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324139/
https://ncbi.nlm.nih.gov/pubmed/28132875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2017.01.013
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