The anti‐ageing hormone klotho induces Nrf2‐mediated antioxidant defences in human aortic smooth muscle cells

Vascular ageing in conditions such as atherosclerosis, diabetes and chronic kidney disease, is associated with the activation of the renin angiotensin system (RAS) and diminished expression of antioxidant defences mediated by the transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Maltese, Giuseppe, Psefteli, Paraskevi‐Maria, Rizzo, Benedetta, Srivastava, Salil, Gnudi, Luigi, Mann, Giovanni E., Siow, Richard C.M.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323877/
https://ncbi.nlm.nih.gov/pubmed/27696667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12996
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