The anti‐ageing hormone klotho induces Nrf2‐mediated antioxidant defences in human aortic smooth muscle cells

Vascular ageing in conditions such as atherosclerosis, diabetes and chronic kidney disease, is associated with the activation of the renin angiotensin system (RAS) and diminished expression of antioxidant defences mediated by the transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Maltese, Giuseppe, Psefteli, Paraskevi‐Maria, Rizzo, Benedetta, Srivastava, Salil, Gnudi, Luigi, Mann, Giovanni E., Siow, Richard C.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323877/
https://ncbi.nlm.nih.gov/pubmed/27696667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12996
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