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MicroRNA‐21 protects against cardiac hypoxia/reoxygenation injury by inhibiting excessive autophagy in H9c2 cells via the Akt/mTOR pathway

MicroRNAs and autophagy play critical roles in cardiac hypoxia/reoxygenation (H/R)‐induced injury. Here, we investigated the function of miR‐21 in regulating autophagy and identified the potential molecular mechanisms involved. To determine the role of miR‐21 in regulating autophagy, H9c2 cells were...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Huang, Zhouqing, Wu, Shengjie, Kong, Fanqi, Cai, Xueli, Ye, Bozhi, Shan, Peiren, Huang, Weijian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323864/
https://ncbi.nlm.nih.gov/pubmed/27680680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12990
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