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Functional and cardioprotective effects of simultaneous and individual activation of protein kinase A and Epac
BACKGROUND AND PURPOSE: Myocardial cAMP elevation confers cardioprotection against ischaemia/reperfusion (I/R) injury. cAMP activates two independent signalling pathways, PKA and Epac. This study investigated the cardiac effects of activating PKA and/or Epac and their involvement in cardioprotection...
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發表在: | Br J Pharmacol |
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Main Authors: | , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
John Wiley and Sons Inc.
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323515/ https://ncbi.nlm.nih.gov/pubmed/28071786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13709 |
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