Temperature preconditioning of isolated rat hearts – a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore

We investigate whether temperature preconditioning (TP), induced by short-term hypothermic perfusion and rewarming, may protect hearts against ischaemic/reperfusion injury like ischaemic preconditioning (IP). Isolated rat hearts were perfused for 40 min, followed by 25 min global ischaemia and 60 mi...

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Detalhes bibliográficos
Main Authors: Khaliulin, Igor, Clarke, Samantha J, Lin, Hua, Parker, Joanna, Suleiman, M-Saadeh, Halestrap, Andrew P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976396/
https://ncbi.nlm.nih.gov/pubmed/17395631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.130369
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