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Genistein and tyrphostin AG556 decrease ultra‐rapidly activating delayed rectifier K(+) current of human atria by inhibiting EGF receptor tyrosine kinase
BACKGROUND AND PURPOSE: The ultra‐rapidly activating delayed rectifier K(+) current I (Kur) (encoded by K(v)1.5 or KCNA5) plays an important role in human atrial repolarization. The present study investigates the regulation of this current by protein tyrosine kinases (PTKs). EXPERIMENTAL APPROACH: W...
Shranjeno v:
| izdano v: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323513/ https://ncbi.nlm.nih.gov/pubmed/28072464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13710 |
| Oznake: |
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