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Synthesis and pre-clinical evaluation of a new class of high-affinity (18)F-labeled PSMA ligands for detection of prostate cancer by PET imaging

PURPOSE: Current clinical imaging of PSMA-positive prostate cancer by positron emission tomography (PET) mainly features (68)Ga-labeled tracers, notably [(68)Ga]Ga-PSMA-HBED-CC. The longer half-life of fluorine-18 offers significant advantages over Ga-68, clinically and logistically. We aimed to dev...

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Bibliografische gegevens
Gepubliceerd in:Eur J Nucl Med Mol Imaging
Hoofdauteurs: Kelly, James, Amor-Coarasa, Alejandro, Nikolopoulou, Anastasia, Kim, Dohyun, Williams, Clarence, Ponnala, Shashikanth, Babich, John W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323493/
https://ncbi.nlm.nih.gov/pubmed/27847991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-016-3556-5
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