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Olfactomedin 2 Regulates Smooth Muscle Phenotypic Modulation and Vascular Remodeling Through Mediating Runx2 Binding to SRF
OBJECTIVE: The objective of this study is to investigate the role and underlying mechanism of Olfactomedin 2 (Olfm2) in SMC phenotypic modulation and vascular remodeling. APPROACH AND RESULTS: Platelet-derived growth factor-BB (PDGF-BB) induces Olfm2 expression in primary SMCs while modulating SMC p...
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| Publicado en: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323295/ https://ncbi.nlm.nih.gov/pubmed/28062493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308606 |
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