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ADAR1-Mediated RNA Editing, A Novel Mechanism Controlling Phenotypic Modulation of Vascular Smooth Muscle Cells

RATIONALE: Vascular smooth muscle (SMC) phenotypic modulation is characterized by the down-regulation of SMC contractile genes. Platelet-derived growth factor-BB (PDGF-BB), a well-known stimulator of SMC phenotypic modulation, down-regulates SMC genes via posttranscriptional regulation. The underlyi...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Fei, Jia, Cui, Xiao-Bing, Wang, Jia-Ning, Dong, Kun, Chen, Shi-You
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961590/
https://ncbi.nlm.nih.gov/pubmed/27199464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309003
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