Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

The tumor necrosis factor-related apoptosis inducing ligand (TRAIL) preferentially induces apoptosis in cancer cells. However, many tumors are resistant to TRAIL-induced apoptosis, and resistance mechanisms are not fully understood. To identify novel regulatory molecules of TRAIL resistance, we scre...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Park, So Jung, Jo, Doo Sin, Jo, Se-Young, Shin, Dong Woon, Shim, Sangmi, Jo, Yoon Kyung, Shin, Ji Hyun, Ha, Ye Jin, Jeong, Seong-Yun, Hwang, Jung Jin, Kim, Young Sam, Suh, Young-Ah, Chang, Jong Wook, Kim, Jin Cheon, Cho, Dong-Hyung
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323206/
https://ncbi.nlm.nih.gov/pubmed/27602754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11781
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