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Role of EGF/ERBB1 in the transcriptional regulation of the prolactin receptor independent of estrogen and prolactin in breast cancer cells

Prolactin receptor (PRLR) and epidermal growth factor receptor (EGFR/ERBB1) have important roles in the physiology of the human breast and in the etiology and progression of breast cancer. Our present studies in MCF-7 cells revealed that EGF induces up-regulation of PRLR via activation of EGFR signa...

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Publicat a:Oncotarget
Autors principals: Kavarthapu, Raghuveer, Dufau, Maria L.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323178/
https://ncbi.nlm.nih.gov/pubmed/27564112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11579
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