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Essential role of endogenous prolactin and CDK7 in estrogen-induced upregulation of the prolactin receptor in breast cancer cells

Our early studies have shown that Estradiol (E(2))/Estrogen Receptor α (ER) in a non-DNA dependent manner through complex formation with C/EBPβ/SP1 induced transcriptional activation of the generic hPIII promoter and expression of the Prolactin Receptor (PRLR) receptor in MCF-7 cells. Subsequent stu...

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Vydáno v:Oncotarget
Hlavní autoři: Kavarthapu, Raghuveer, Dufau, Maria L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432340/
https://ncbi.nlm.nih.gov/pubmed/28423697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16040
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