A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia

Natural killer (NK) cell neoplasms are characterized by clonal proliferation of cytotoxic NK cells. Since there is no standard treatment to date, new therapeutic options are needed, especially for NK aggressive tumors. Fyn tyrosine kinase has a key role in different biological processes, such as cel...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Laurenzana, Ilaria, Caivano, Antonella, Trino, Stefania, De Luca, Luciana, Rocca, Francesco La, Simeon, Vittorio, Tintori, Cristina, D'Alessio, Francesca, Teramo, Antonella, Zambello, Renato, Traficante, Antonio, Maietti, Maddalena, Semenzato, Gianpietro, Schenone, Silvia, Botta, Maurizio, Musto, Pellegrino, Vecchio, Luigi Del
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323146/
https://ncbi.nlm.nih.gov/pubmed/27566560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11496
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