Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes.
Defensins are cationic, cysteine-rich peptides (Mr = 3500-4000) found in the cytoplasmic granules of neutrophils and macrophages. These peptides possess broad antimicrobial activity in vitro against bacteria, fungi, tumor cells, and enveloped viruses, and they are believed to contribute to the "oxyg...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.210 |
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