Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes.

Defensins are cationic, cysteine-rich peptides (Mr = 3500-4000) found in the cytoplasmic granules of neutrophils and macrophages. These peptides possess broad antimicrobial activity in vitro against bacteria, fungi, tumor cells, and enveloped viruses, and they are believed to contribute to the "oxyg...

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Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Kagan, B L, Selsted, M E, Ganz, T, Lehrer, R I
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1990
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.210
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