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p27(kip1) expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms

The tumor suppressor protein p27(Kip1) plays a pivotal role in the control of cell growth and metastasis formation. Several studies pointed to different roles for p27(Kip1) in the control of Ras induced transformation, although no explanation has been provided to elucidate these differences. We rece...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Pellizzari, Ilenia, Fabris, Linda, Berton, Stefania, Segatto, Ilenia, Citron, Francesca, D'Andrea, Sara, Cusan, Martina, Benevol, Sara, Perin, Tiziana, Massarut, Samuele, Canzonieri, Vincenzo, Schiappacassi, Monica, Belletti, Barbara, Baldassarre, Gustavo
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323099/
https://ncbi.nlm.nih.gov/pubmed/27579539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11656
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