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A Simple and Sensitive High-Content Assay for the Characterization of Antiproliferative Therapeutic Antibodies

Monoclonal antibodies (mAbs) have become a central class of therapeutic agents in particular as antiproliferative compounds. Their often complex modes of action require sensitive assays during early, functional characterization. Current cell-based proliferation assays often detect metabolites that a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:SLAS Discov
Main Authors: Stengl, Andreas, Hörl, David, Leonhardt, Heinrich, Helma, Jonas
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322830/
https://ncbi.nlm.nih.gov/pubmed/27909235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116677821
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